2022 -

I founded The BioML Society, a student-led research group, with my colleague Aaron Feller in Spring 2023. As of Oct 2024 we have 18 completed or ongoing projects with various faculty.
In Fall 2023 I designed and co-taught a lecture series on machine learning for biochemical applciations. This series went on to become an official course taught by Dr. Claus Wilke in Fall 2024.
In Summer 2024 I organized a worldwide protein design competition with Aaron Feller, Daryl Barth, and Phillip Woolley. This competition was covered in Nature and is currently ongoing.
In Fall 2023 I designed and co-taught a lecture series on machine learning for biochemical applciations. This series went on to become an official course taught by Dr. Claus Wilke in Fall 2024.
In Summer 2024 I organized a worldwide protein design competition with Aaron Feller, Daryl Barth, and Phillip Woolley. This competition was covered in Nature and is currently ongoing.
2022 -

My PhD is focused on using AI for small molecule discovery and protein design. I am co-advised by Andrew Ellington and Edward Marcotte.
2020 - 2022

I was a research associate at Beyond Meat where I worked on projects in analytical chemistry (GCMS, lipids), lab automation (liquid handlers, data processing, LIMS), and flavor chemistry.
2016 - 2020

BS in Chemical & Biological Engineering at the University of Colorado. Research on Organic Synthesis in Wei Zhang's lab and microfluidic simulations in Robert Davis' lab.
Publications
Mining patents with large language models elucidates the chemical function landscape | Digital Discovery 2024
Clayton Kosonocky, Claus Wilke, Edward Marcotte, Andrew Ellington
Clayton Kosonocky, Claus Wilke, Edward Marcotte, Andrew Ellington
Using alternative SMILES representations to identify novel functional analogues in chemical similarity vector searches | Patterns 2023
Clayton Kosonocky, Aaron Feller, Claus Wilke, Andrew Ellington
Clayton Kosonocky, Aaron Feller, Claus Wilke, Andrew Ellington
Evolving to Evolve, Dan Tawfik’s Insights into Protein Engineering | Biochemistry 2023
Clayton Kosonocky, Andrew Ellington
Clayton Kosonocky, Andrew Ellington
Directed evolution of generalist biosensors for single ring aromatics | bioRxiv 2022
Hannah Cole, Clayton Kosonocky, Mason Schechter, Jimmy Gollihar, Andrew Ellington, Simon d'Oelsnitz
Hannah Cole, Clayton Kosonocky, Mason Schechter, Jimmy Gollihar, Andrew Ellington, Simon d'Oelsnitz